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Pleasantville Seniors Present Scientific Research

Doug Hughes, Jennifer Grom, Clare and Connor Eichinger and Kyle Cohen presented their scientific research at the Pleasantville High School Science Research Symposium on June 1.

Hughes presented his research on IgA Nephropathy, an autoimmune disease which can lead to renal failure. Nephropathy is diagnosed by a renal biopsy which can be costly. Hughes explained how an antibody, IgA (immunoglobulin A) may actually have a lesser chance of nephropathy than their healthy counterparts. Hughes will be attending University of Rochester in the fall.

Grom presented her research on Medulloblastomas, deadly brain tumors that typically arise in young children. These tumors are not developed until 12 months of age. Grom’s research goal was to find a more efficient treatment for Medullloblastomas. Grom will be attending SUNY Geneseo this fall.

Cohen displayed his research on Reactive Attachment Disorder in Ethiopia and in the Bronx. Cohen traveled to Ethopia last summer to conduct his research on 25 orphans and compared the data to 25 Bronx children at the New School for Social Research in New York City. Cohen is attending Syracuse University this fall.

Clare Eichinger presented her research on the antimicrobial effects of Entamoeba histolytica, a single-celled eukaryotic human parasite prevalent in third-world and developing countries, which results in approximately 100,000 deaths every year. Clare Eichinger is currently enrolled in a 7-year medicine program at Boston University starting this fall.

Connor Eichinger presented research on a malaria vaccine. Eichinger examined the role of nitric oxide and DNA proteins with malarial parasites (mosquitoes) in the immune response leading to malaria. He found that by deleting a part of the gene coding of a DNA plasmid, it can be transfected into the parasite so it can induce an immunity to malaria.

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